[5][6] This gene encodes a member of the Tubby family of bipartite transcription factors.

The encoded protein may play a role in obesity and sensorineural degradation.

The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis.

Two transcript variants encoding distinct isoforms have been identified for this gene.

This article on a gene on human chromosome 11 is a stub.