In 2017, Takeoff released the single "Intruder" as a non-album single and was featured on his uncle Quavo's collaborative project, Huncho Jack, Jack Huncho, with fellow rapper Travis Scott, on the song "Eye 2 Eye".

In that year, he also collaborated with Scottish DJ Calvin Harris for his Funk Wav Bounces Vol.

In 2018, he released his debut studio album The Last Rocket via Quality Control Music, Capitol Records and Motown, on November 2, 2018.

The album peaked in the top 30 of the Netherlands and Norway charts at 29th and 24th respectively while placing at 42nd and 51st on the United Kingdom and Sweden charts.

The album spawned the single "Last Memory", which appeared on the US and Canadian charts, while a non-single song from the album "Casper" appeared on the New Zealand Hot chart.