Takilma is an unincorporated community and census-designated place (CDP) in Josephine County, Oregon, United States, 10 miles (16 km) south of Cave Junction.

According to Oregon Geographic Names, Takilma was originally called "Taklamah", probably by Col. T. W. Draper of the Waldo Copper Company for an Indian chief.

In the winter of 1968, hippies began moving into the Illinois Valley as part of the back to the land movement, notably into Takilma.

The 1987 Longwood fire forced the clinic, now called the Siskiyou Community Health Center, to move into Cave Junction.

[8] The Jefferson Baroque Orchestra was formed in 1994 by Takilma resident Jim Rich, and is now in its 20th season, with performances in Grants Pass and Ashland.