[2] Azmi portrayed a troubled doctor in the tele-series, Jeevanrekha and as a young widow in telefilm Rao Saheb (1986) directed by Vijaya Mehta.

[4] She received her first nomination for the Filmfare Award for Best Supporting Actress for her performance in the drama Pyari Behna (1985).

[5] The psychological thriller Dushman (1998) starring Kajol and Sanjay Dutt, saw her play Dr. Poornima Sehgal, a psychologist, earned her a third nomination for the Filmfare Award for Best Supporting Actress.

In 2015, she appeared alongside Ranveer Singh, Deepika Padukone and Priyanka Chopra in Sanjay Leela Bhansali's historical romantic drama Bajirao Mastani.

[7] Her performance in the domestic drama Thappad (2020) received high critical acclaim and earned her a fifth nomination for the Filmfare Award for Best Supporting Actress.