She and her husband, Daniel Snyder, owned the Washington Commanders of the National Football League (NFL) from 1999 to 2023.

She launched a charitable foundation in 1999, contributing more than $31 million to local community initiatives, and also helped establish the NFL's "Think Pink" breast cancer awareness campaign.

[3] Snyder partnered with Zeta Tau Alpha to co-found the THINK PINK campaign for breast cancer awareness within the National Football League in 1999.

[10][11] In July 2023, the Commanders were sold to a group led by Josh Harris for $6.05 billion, the largest sales transaction for a sports franchise in history.

[1] She met American businessman Daniel Snyder on a blind date in 1993; they married in April 1994.