This article deals with the entire length of the corridor for sake of completion, as well to avoid confusion between declarations.

The Tapleys Hill Road corridor runs north–south through Adelaide's western and south-western suburbs, to the mouth of the Onkaparinga River at its southern end.

Prior to an upgrade in the 1990s, Tapleys Hill Road's southern end was joined to Anzac Highway, about 100 metres to the west of where it currently lays.

The old roadway still exists, now named Old Tapleys Hill Road, and is rarely used as a through route, servicing mainly residents of the area.

The road forms the initial half of the traditional route from Port Adelaide to Tapley's Hill.