From 2001 to 2003, he worked as a leading specialist for Armenia's State Committee of Real Estate Cadastre in the territorial unit of Nor Nork, and later became the head of the department.

[1] Taron Margaryan has served as the mayor of Yerevan since 15 November 2011 after being elected by the City Council and succeeded Karen Karapetyan after his resignation.

[2] In 2013, he earned a position at the top of the list of candidates for the Republican Party of Armenia's 2013 municipal elections with the leading slogan "Better Yerevan.

After Nikol Pashinyan became prime minister of Armenia during the velvet revolution in April 2018, city hall was raided and the Yerevan Fund which Margaryan was head of was implicated in large-scale corrupt practices.

[4] Then a video came out highlighting Margaryan's vast and undeclared wealth and businesses[5] which received widespread attention and well over a hundred thousand views.

In 2014, the prestigious Rutgers University of Public Affairs and Administration E-School Institute located in the United States rated Yerevan as one of the fastest-growing cities in the world.

In the latter case, although the building's privatization and construction permit existed before Taron Margaryan took office, the community nonetheless criticized the municipality for failing to prevent the destruction.

[16] Numerous protests took place during Taron Margaryan's first few years in office on behalf of residents living in buildings considered to be dangerous of the 4th-category.

In December 2015, Taron Margaryan handed out keys to new apartments to residents living in the dormitories located on Sisakyan 3, 4, and 127/1, Nor Aresh 35, Artsakh Street 10/2.

[17] During Taron Margaryan's years in office, he intensified Yerevan's international relations with other neighboring and capital cities, organizing mutual visits regularly.

Sister cities are included in the scope of cooperation in trade, science, technology, culture, health, tourism, construction, and other industries.

According to the declaration submitted to the Ethics Committee, as of 2016, Taron Margaryan has 250 million AMD, translating to about 500k USD and 500k EUR.