Siradeghyan was born on November 13, 1946, in the village of Koti (formerly called Shavarshavan) in northeastern Armenia, near the Azerbaijani border.
[3] Siradeghyan was appointed the Minister of Interior Affairs in 1992 by President Levon Ter-Petrosyan, a post he held until 1996.
[9] He also played a key role in the forcible crackdown against Vazgen Manukyan's supporters' protests after the controversial 1996 presidential election.
[10] In an interview in January 1999, Siradeghyan admitted that the government had resorted to vote-rigging to secure Ter-Petrosyan's victory without a runoff election and stated that after the crackdown, President Ter-Petrosyan fell into a three-month depression and wanted Siradeghyan and Defense Minister Vazgen Sargsyan to resign.
[4][14] In February 1999 the Deputy Minister of the Interior and National Security and commander of Armenia's internal troops, General Artsrun Makaryan was shot dead, "prompting speculation that he had been killed to prevent him from giving evidence against Siradeghyan.
[14] Siradeghyan left Armenia in early April 2000[14] after the National Assembly lifted his parliamentary immunity to allow for his criminal prosecution.
[14][20] Armenia's former Foreign Minister Alexander Arzoumanian replaced him as leader of the Pan-Armenian National Movement in December 2000.
[21][22] Following his disappearance, Siradeghyan wrote a number of political articles for the newspaper Haykakan Zhamanak under the pen name Avetis Harutyunyan, which were later published in a collection titled Gyadaneri zhamanakě (The era of rascals).
[27] During parliamentary talks on Siradeghyan's issue, Hovik Abrahamyan, the Speaker of the National Assembly stated "I’m not expecting him; if he wants to come back, let him come, it’s his business.
"[24] Hayk Babukhanyan, MP from the Republican Party of Armenia, stated in August 2012 that Siradeghyan "should face a trial" and "should carry the responsibility for the crimes he committed."
[28] Siradeghyan's supporters credit him with fighting rampant organized crime in Yerevan during his time as minister of internal affairs and praise his written works.
His remains were buried in his home village of Koti on 4 December 2021 after a wake at the Yerevan Opera Theatre.