[1] Born in Khndzoresk, now located in Syunik Province, Sazandaryan grew up in Baku, singing as a soloist in the school choir from the age of 10.
She then returned to Armenia where she studied at Yerevan's school of music and drama under Sargis Barkhudaryan.
She is remembered in particular for playing Parandzem in Tigran Chukhajian's opera Arshak II and Tamar in Armen Tigranian's David Bek.
[1] She gained an extensive reputation, performing in the principal cities of the USSR as well as in Persia, Sweden, Tunisia, Hungary, Syria (1956), Belgium (1958, 1962), Greece (1959), Czechoslovakia (1960), and France (1963).
[2] Sazandaryan was honoured with many awards including the Stalin Prize (1951) and the Order of St. Mesrop Mashtots (1997).