She was a science and climate reporter for The New York Times, and has also written for several publications and outlets including The Atlantic, The Washington Post, Vanity Fair, and Bloomberg.

[2] She and her two siblings, Rose and Jack, were primarily raised in Manhattan's Upper East Side, and has also spent significant time at their maternal grandmother Jacqueline's estate at Martha's Vineyard growing up.

[2][6] She was also a member of the senior society Mace and Chain,[7] and was awarded the Charles A. Ryskamp Travel Grant for her research project which "explored the communities that grew out of the relationship between runaway slaves and coastal New England Native American tribes, particularly on Martha's Vineyard in the nineteenth century.

In 2014, she wrote a story about a dead bear cub found in Central Park which was later revealed in 2024 to have been placed there by her relative Robert F. Kennedy Jr..[11] Schlossberg responded to the revelation, saying "like law enforcement, I had no idea who was responsible for this when I wrote the story.”[12]Schlossberg was a science and climate reporter for the Times before leaving in 2017.

[17] Schlossberg has taken part in presenting the annual Profile in Courage Award at the John F. Kennedy Presidential Library and Museum in Boston,[18] and has accompanied her mother Caroline in her engagements as ambassador in Japan and Australia.