Born in the family of Kiev advocate Lev Kupernik, Tatiana Shchepkina-Kupernik was a granddaughter of famous Russian actor Mikhail Shchepkin and Elena Dmitrievna who was a Turkish captive during the Siege of Anapa.

Her poem At Homeland - From the fallen strongholds of Port-Arthur... («На родине» - «От павших твердынь Порт-Артура...») written at 1905 quickly became known nationwide.

She produced several well-known Russian translations of Edmond Rostand and Maurice Maeterlinck plays.

Shchepkina also translated the works of Lope De Vega, William Shakespeare, John Fletcher, Molière, Carlo Goldoni, Richard Brinsley Sheridan and Lewis Carroll's Alice's Adventures in Wonderland into Russian.

She composed poetic plays of her own, mostly in one act (Revenge of Amur, Eternity in a Moment, Lady with Violets, Happy Women, etc.).