[1] Romano began her career performing voice-over roles in animations, including PBS's WordWorld and various commercials.

[3][4][5] The film was selected for the Frontières Platform at the Festival de Cannes in April of that year.

[6] Later in 2018, she starred as one of the protagonists in Snapchat's Snap Original, Class of Lies, a series based on two college best friends and roommates who solve cold cases on their crime podcast.

[7] The series was the recipient of the Writers Guild of America Awards for Best Short Form New Media and received over 20 million viewers.

[8][9] In 2021, she appeared in two films: Nineteen on Fire, alongside Euphoria's Alexa Demie, and Year One.