Fatma was born on 10 March 1949 to Mohammad Abdul Qaiyoom and Asghari Khatoon in Bilgram, a village in Hardoi district of Uttar Pradesh, India.

[3] She attended Aligarh Muslim University and obtained M.A., M.Phil., and Ph.D.[4] She started working as associate professor in Political science in the department of education [where?].

[7] She and her husband were accused of procuring multiple birth certificates made in Rampur and Lucknow for their son Abdullah to get two passports.

[8] Tazeen Fatma, along with her son Abdullah Azam Khan, got a notice for encroaching upon farmers' land to construct Mohammad Ali Jauhar University on 9 September 2019.

[9] She was also booked under section 447 and 184 of Indian Penal Code for encroaching on government land to build Humsafar resort.