The Teatro Colón was visited by the foremost singers and opera companies of the time, who would sometimes go on to other cities including Montevideo, Rio de Janeiro and São Paulo.

[6][7] Throughout its history the main figures of opera, classical music and world ballet have performed in the Colón theater, such as Arturo Toscanini, Vaslav Nijinsky, Luisa Tetrazzini, Enrico Caruso, Conchita Supervia, Regina Pacini, Anna Pavlova, Maya Plisetskaya, Margot Fonteyn, Mikhail Barishnikov, Antonio Gades, Richard Strauss, Igor Stravinsky, Camille Saint-Saens, Manuel de Falla, Aaron Copland, Herbert von Karajan, Leonard Bernstein, Mstislav Rostropovich, Zubin Mehta, Maria Callas, Renata Tebaldi, Leontyne Price, Ana Serrano Redonnet, Celia Torra, Yehudi Menuhin, Pau Casals, Rudolf Nureyev, Maurice Béjart, Plácido Domingo, José Carreras, Luciano Pavarotti, Lily Pons, Marina de Gabaráin, Victoria de los Ángeles, Reri Grist, Montserrat Caballé, Kiri Te Kanawa, among others, and Argentine artists such as Adelaida Negri,[8] Héctor Panizza, Alberto Ginastera, Jorge Donn, Norma Fontenla, José Neglia, Olga Ferri, Julio Bocca, Maximiliano Guerra, Paloma Herrera, Daniel Barenboim, Martha Argerich, Astor Piazzolla, Aníbal Troilo and Osvaldo Pugliese.

In the last decade other popular artists such as Chris Cornell, Katherine Jenkins, Sarah Brightman, Joss Stone, Branford Marsalis, play here.

In 1946, Peronism promoted a policy of openness to popular music and greater democratisation of the public, which was reverted after its overthrow in 1955 and again resumed when democracy recovered in 1983.

The first Teatro Colón was designed by Charles Pellegrini, and proved to be a successful venue for over 30 years, with 2,500 seats with the inclusion of a separate gallery reserved only for people who were in mourning.

This theater was closed on 13 September 1888 to step aside for a new improved building, which was opened twenty years later on Libertad street, overlooking Plaza Lavalle.

The auditorium is horseshoe-shaped, has 2,487 seats (slightly more than the Royal Opera House in Covent Garden, London), standing room for 1,000 and a stage which is 20 m wide, 15 m high and 20 m deep.

The original auditorium "had eight boxes with metal grilles and a separate entrance, so that those in mourning could still attend performances, but remain dignifiedly sequestered from public view".

The cornerstone of the present Teatro Colón was laid in 1889 under the direction of architect Francesco Tamburini and his pupil, Vittorio Meano, who designed a theatre in the Italian style on a scale and with amenities which matched those in Europe.

The building was finally completed in 1908 under the direction of the Belgian architect Julio Dormal who made some changes in the structure and left his mark in the French style of the decoration.

The wounded were carried off as best as possible, and the room was emptied by the cries of fury, and the material damage repaired during the day which followed, not a woman of society missed the representation of the morrow.

In recent years, given the political and economic circumstances of Argentina, the Teatro Colón has suffered considerably, but a period of slow recovery began.

The theatre underwent massive phased remodelling of both interior and exterior, initially while the house was still open, but production activities ceased at the end of December 2006 to allow full refurbishment.