He played for the Philadelphia Phillies, Pittsburgh Pirates, St. Louis Cardinals, Chicago Cubs, Los Angeles Dodgers, Cincinnati Reds, Milwaukee Brewers, and Kansas City Royals.

[2] Savage made his major league debut with the Phillies on April 9, 1962, in a 12–4 road win over the Cincinnati Reds at Crosley Field.

Pinch-hitting for Wes Covington against Bob Miller, he grounded out but stayed in the game, playing left field.

After grounding out again, in the seventh inning he notched his first major league hit and RBI with a single off pitcher Dave Hillman that drove in Tony Gonzalez.

[5] After the 1964 season, the Pirates traded Savage and Earl Francis to the St. Louis Cardinals for Jack Damaska and Ron Cox.

Savage had perhaps the best season of his career in 1970, playing in 114 games and batting .279 with 12 home runs, 50 RBI and a .402 slugging percentage in 343 plate appearances.