Originally, the Kinsmen had the idea to have a car raffle to raise funds to help with all the requests for assistance they received but the government wouldn't allow it.

Early broadcasts of the telethon featured a mix of national and international celebrities such as John Allan Cameron, Gloria Loring, Alan Thicke, the Irish Rovers, Arte Johnson of Laugh-In, Bob McGrath of Sesame Street, game show personality Jim Perry, his daughter Erin Perry, singer and TV host Blake Emmons (who was the telethon's de facto host during the first few years, a post later taken over by Thicke in the 1980s and most recently by Beverley Mahood and Brad Johner), pianist Frank Mills and Saskatchewan-born motivational speaker Alvin Law.

The current record is held by the 46th Telemiracle (2022); the total of $8,002,722 included a bequest of $1,779,771.20, the largest pledge—bequest or otherwise—in the telethon's history.

A convention was booked in Regina for the days leading up to the telethon, meaning that the usual setup time was not available.

[2] Shown annually on CTV affiliates, the broadcast starts at 9 pm local time on the first Saturday in March (though for the first half of its history, it was often scheduled in February).

The broadcast always concludes with "O Canada" and a balloon and confetti drop during which time some of the volunteers take to the stage to celebrate; up through 2010, a rendition of "With a Little Help from My Friends" was included with the closing festivities.

[citation needed] While the show is now carried only on Saskatchewan CTV stations, the production crew is composed of approximately 200 volunteers representing several broadcast networks, many traveling from outside of the province.

The Countdown Show is hosted by two members of the national cast and features 12 Saskatchewan Talent performances.

Since 2021, Telemiracle has been held in a modified format due to the COVID-19 pandemic, with no live audience and primarily pre-recorded performances.

At the 42nd Telemiracle in 2018, a brand new record total was raised, thanks in large part to two individual bequeaths of over $1 million each.