In June 2012 when asked about a sequel to Tenacious D in The Pick of Destiny, Black stated that the band had "found a loophole with the internet and animated shorts.

"[2] The project was a fantasy for Black and Gass for a few years, until the Donald Trump presidential campaign inspired them to start writing a post-apocalyptic comedy in 2016.

[3] The project was assembled by Black physically drawing each frame with markers and notepads, with longtime Tenacious D bassist and producer John Spiker scanning and digitalizing the images.

[4] In December 2017, whilst on Kerrang Radio promoting Jumanji: Welcome to the Jungle, Black stated that the title of the animated series would be called Tenacious D in Post-Apocalypto.

[6] On May 6, 2018, during Tenacious D's performance at the Shaky Knees Music Festival, Black asked the audience if anyone had seen The Pick of Destiny, and that "part two is coming out in October.

[11] On November 8, 2018, all of the episodes were uploaded as one video branded "full movie"[12] which, as of February 2024, has since been removed from YouTube for violating their policy on nudity or sexual content.

The series was partially screened as part of the band's Post-Apocalypto Tour, which commenced on November 3, 2018, at the Kings Theatre in Brooklyn, and finished on February 26, 2020, at the Zénith Paris.