It travels to the north as Main Street into downtown and then turns northeast as Cumberland Drive and leaves Whitwell.

It then ascends to the top of the Cumberland Plateau and passes through primarily rural terrain, where it passes through Griffith Creek, until it reaches Grundy County.

[2] SR 108 continues north through rural terrain until it enters the town of Palmer and passes through its downtown area.

Approximately 1 mile (1.6 km) past the SR 56 intersection, it leaves Coalmont and enters rural terrain again, where it comes to an intersection and becomes concurrent with SR 50 and turns back north on SR 50 east.

Just after leaving Altamont, it turns back north and continues on a northerly track through a mix of hills and farmland until it crosses into Warren County.