[2] It heads southeast through wooded areas to cross into Henderson County and pass through farmland for several miles to enter Sardis, where it has an intersection with SR 421 and has a short concurrency with SR 104.

The highway then leaves Sardis and winds its way northeast through a mix of farmland and wooded areas to enter Scotts Hill and come to an intersection with SR 114 in downtown.

SR 114/SR 201 then leave Scotts Hill and wind their way north through a mix of farmland and wooded areas for several miles before SR 201 splits off goes east.

[3] SR 201 continues east through rural areas before crossing into Decatur County and coming to an end shortly thereafter at an intersection with SR 202, just northwest of Decaturville.

[4] The entire route of SR 201 is a two-lane highway.