[1] The event was part of the qualification criteria for the tennis tournament at the 2012 Summer Olympics.

The winners of the five competitions had priority entrance into the tennis event, if they were not directly qualified and were near the top 56 in the world.

[1] The mixed doubles event was being held for the first time since the 1995 Pan American Games in Mar del Plata, because the event was added to the tennis program of the 2012 Summer Olympics in London, Great Britain.

[2] *   Host nation (Mexico)Countries can enter a maximum of six athletes, three men and three women.

Seeding was based on ATP and WTA rankings at the time of the draw (October 16).