[3] The Center for Ethics has 6 Nobel Peace Laureates as its founding members and its programs run in 5 countries while poised for a global reach.

He founded the Prajnopaya Institute to create an avenue for critical study and practice of Buddhist philosophy within Europe and North America.

Turing Prize winner Edward Feigenbaum said that he was encouraged by this novel "ethics as optimization" approach to Cognitive Computing and AI as presented by Priyadarshi at a summit in Napa, California.

[6] Primary institutions overseeing this work are MIT Media Lab and the Berkman Klein Center for Internet & Society at Harvard University.

He encouraged the audience to begin thinking of nurturing ethics and empathy (as well as its "upgraded forms" such as kindness and compassion) as civic responsibility without which any democratic system is at threat.

Having been exposed to the dangers of religious fanaticism and violence early on, Priyadarshi has been instrumental in conflict resolution processes in India and Sri Lanka.

He has made his admiration for Francis of Assisi quite public and travels to Italy frequently to engage in spiritual dialogue with Christian monastic communities.

[10][11] He was a project advisor to a team of architects from MIT, Harvard Graduate School of Design, and University of Cambridge to develop Tsunami Safe(r) Houses, low cost high resistant homes for families in Sri Lanka.

He served as the founding member and director of the Vishwa Shanti Stupa (World Peace Pagoda Projects) in New Delhi and Sarnath (Varanasi), India.

Flutist and Musician Paul Horn said "The Venerable Tenzin Priyadarshi's soft powerful chanting, in a warm lush instrumental setting, offers a deep spiritual experience for the listener.

Krishna Das adds "With a great depth of Devotion that is lit with Wisdom, Tenzin Priyadarshi creates a beautiful offering of Ancient Buddhist Prayers."

Pulitzer Prize–winning author of The Emperor of All Maladies, Siddhartha Mukherjee says “Running Toward Mystery is not merely a book, but an experience, a biography, a formula for living, and a manifesto for a new kind of exploration of life.

I could not put it down.”[19] In September 2024, Priyadarshi released “Solivagant: Tales of Solitude and Wonderment,” a book of collection of photographs accompanied by exhibitions in Singapore and Hanoi, Vietnam.