Tepeji del Rio has many industrial complexes with companies such as Beaver Manufacturing, Procter and Gamble, Kaltex, Arteche, Zaga, PPG and Pilgrims Pride.

Amanali Country Club & Nautica has a golf course situated in the northern part of the town overlooking Lake Requena, along with associated residential areas.

The town is also known for being the birthplace of Mexican footballer Raúl Jiménez.

As of 2020, Tepeji is governed by Salvador Jiménez Calzadilla, member of the Institutional Revolutionary Party.

This article about a location in the Mexican state of Hidalgo is a stub.