Terazosin

Terazosin, sold under the brand name Hytrin among others, is a medication used to treat symptoms of an enlarged prostate and high blood pressure.

[1] Common side effects include dizziness, headache, feeling tired, swelling, nausea, and low blood pressure with standing.

[1] Severe side effects may include priapism and low blood pressure.

[3] In 2021, it was the 234th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

[4][5] Reaction of piperazine with 2-furoyl chloride followed by catalytic hydrogenation of the furan ring leads to 2.

Terazosin synthesis: [ 6 ]