In that historical period, the village, as well as the entire area of the island was affected by strong trade and military, given the presence of two important roads of communication that mark the territory: one between the cities of Bergamo and Milan to south, and another that linked the capital Orobico in Como in the north.

However, in the late Middle Ages that saw this situation as a town Terno pù important proved to be a profoundly destabilizing element, given the willingness of different lordships to gain dominance over it: many battles between the Guelphs and Ghibellines, and later between the armies of Milan and Venice, put a strain on the people who lived centuries of poverty, so that the island was called "the triangle of hunger."

In this sense the description is very clear in a document of time: "Here there are no traffic nor merchandise, people are poor by lavoradori terre et bracenti, such grains do not collect a penalty for their living, and they have no privilege, but subject to all the tributes to datii et ... " Is there any news of devastation and looting, the main one being perpetrated in 1406 by troops of the leader Bartolomeo Colleoni.

The situation seemed to improve with the arrival of the Republic of Venice, inserting Terno district called Quadra Island to establish it as the capital and seat of the mayor.

Repeatedly subjected to renovation and rebuilding, still retains elements of the original structure, and a neo-Gothic facade and numerous sculptures and paintings, among which they include some of Enea Salmeggia and Bartolomeo Nazari.