[citation needed] Leo-Wilson placed second in the first round of the 2022 Republican Primary election for District 23, advancing to the runoff along with Greg Abbott's endorsed candidate Patrick Gurski.

In her first term, she served on the Juvenile Justice & Family Issues and Pensions, Investment & Financial Services committees.

[10] Leo-Wilson was born in Worthington, Minnesota on January 3, 1960, to a family of crop farmers.

She and her new family moved to the Galveston beach; she has said they "love the coastal vibe" of the city.

They quickly became enmeshed in the city's politics, including involvement in the Galveston Chamber of Commerce.