According to Neese, she briefly attended the University of Oklahoma, studying secretarial science with the intention of being an administrative assistant.

[9][10] GrassRoots Impact provides a communications strategy for corporations and government agencies to effectively reach out to women and minorities in business.

[18][19] In the June 30, 2020, Republican primary, she placed first among a field of nine candidates, but was then defeated in a runoff election by state senator Stephanie Bice.

This led to her being appointed by President George H. W. Bush in the 1990s to be a Commissioner to the National Advisory Council on Indian Education, whose members must be Native American.

Similarly, President George W. Bush nominated Neese to lead the U.S. Mint in 2005 at least partly because of her claim to have roots in the Cherokee Indian Community.

In an article published at the time (of President George W. Bush), Neese stated that "her roots to the Cherokee Indian Community run deep".

[22] In 2005, Neese was requested to decline a government appointment from President Bush after training tapes had been uncovered in which she instructed her employees to lie and use unethical behavior.

At the time, Neese — who had been a large Bush fundraiser — claimed she was declining her appointment as Director of the U.S. Mint for family reasons; the allegation of impropriety was not made until 2019.