[2] Common side effects include pain at the site of injection and fever.
[1] Allergic reactions including anaphylaxis may rarely occur.
[1] There is also a very low risk of the spread of infections such as viral hepatitis and HIV/AIDS with the human version.
[4] Since the tetanus toxin permanently binds to human tissues, only unbounded molecules can be neutralized by the immunoglobulin.
[5] The horse version is not typically used in the developed world due to the risk of serum sickness.