Tetlin National Wildlife Refuge is a dynamic landscape made up of forests, wetlands, tundra, lakes, mountains and glacial rivers bounded by the snowy peaks of the Alaska Range.

This upper Tanana River valley has been called the "Tetlin Passage," because it serves as a major migratory route for birds traveling to and from Canada, the lower 48 and both Central and South America.

An estimated 116 species breed on Tetlin during the short summer, when long days and warm temperatures accelerate the growth of plants, insects and other invertebrates, providing a ready source of rich foods for nesting birds.

Dall sheep dot the higher slopes while Alaskan moose feed upon the tender new growth that springs up in the wake of frequent lightning caused fires.

Wolf packs, turkey vulture, Canadian lynx, tundra swan, red fox, peregrine falcon, coyote, beaver, golden eagle, marten, six species of owls, snowshoe hare, osprey, trumpeter swan, muskrat, bald eagle, river otter, grizzly bears and black bears and members of three different caribou herds range over the refuge.