It was originally designated by 1933 along its current route, except that it extended southwest from Navasota to Brenham.

The routing between Madisonville and Navasota was originally set before the state's highway system was started.

The route remained a minimally serviced dirt road until the early 1930s, when paving occurred.

Numerous reroutings occurred during the next 70 years, including being rerouted away from the town of Washington on February 24, 1953 (the old route through Washington was redesignated as FM 912) and the eventual transferral of the section between Brenham and Navasota back to State Highway 105 on February 28, 1973.

It then travels through the western side of Anderson, passing a block west of the Grimes County Courthouse.