The diatom requires a high enough concentration of CO2 in order to utilize C4 metabolism (Clement et al.

[2] The clone of T. pseudonana that was sequenced is CCMP 1335 and is available from the National Center for Marine Algae and Microbiota at Bigelow Laboratory for Ocean Sciences.

This clone was originally collected in 1958 from Moriches Bay (Long Island, New York) and has been maintained continuously in culture.

Its biosilica cell wall is divided into two halves, which are joined together by girdle bands, giving them a cylindrical shape or making them appear as a Petri dish.

[5][6] The valve is made up of silica ribs that radiate from the center with many 18 nm diameter nanopores between them.

[8] Their cell walls have been reported to mostly have low degree of silicification; however, their rims and ribs are highly silicified.

The silicification process involves three categories of molecules: silaffins, which are highly post-translationally modified phosphoproteins; long chain polyamines (LCPAs); and silacidins, which are acidic proteins.

[4] During valve synthesis, mRNA levels for silaffin 3 increase and lead to the formation of the base layer.

[11] Thalassiosira pseudonana and the heterotrophic alphaproteobacterium Ruegeria pomeroyi form a chemical symbiosis in coculture.

[12] A metabolic survey of the association between the bacterium Dinoroseobacter shibae and T. pseudonana showed that the bacterium has minimal impact on the growth of T. pseudonana, but it causes metabolic changes by upregulating the intracellular amino acids and amino acid derivatives of the diatom.

[13] It has been demonstrated that under conditions of environmental instability and extreme warming, biofilm formation can accelerate the evolutionary responses of T.

[14] Meksiarun, Phiranuphon; Spegazzini, Nicolas; Matsui, Hiroaki; Nakajima, Kensuke; Matsuda, Yusuke; Sato, Hidetoshi (January 2015).

"In Vivo Study of Lipid Accumulation in the Microalgae Marine Diatom Thalassiosira pseudonana Using Raman Spectroscopy".

"Photosynthetic and molecular responses of the marine diatom Thalassiosira pseudonana to triphenyltin exposure".

"Positive feedbacks between bottom-up and top-down controls promote the formation and toxicity of ecosystem disruptive algal blooms: A modeling study".

Delalat, Bahman; Sheppard, Vonda C.; Ghaemi, Soraya Rasi; Rao, Shasha; Prestidge, Clive A.; McPhee, Gordon; Rogers, Mary-Louise; Donoghue, Jaqueline F.; Pillay, Vinochani; Johns, Terrance G.; Kroeger, Nils; Voelcker, Nicolas H. (2015).