Thalassodromidae (meaning "sea runners", due to previous misconceptions of skimming behavior; they are now thought to be terrestrial predators) is a group of azhdarchoid pterosaurs from the Cretaceous period.

Though the relationship with tapejarids remains supported by many studies, it has been proposed that it is preferable to retain them as a distinct family for consistency of communication.

[2] This arrangement would later be supported by British paleontologists David Martill and Darren Naish, who deemed Tapejaridae to be paraphyletic (unnatural), and found both Thalassodromeus and Tupuxuara as sister taxa to Azhdarchidae.

[3] In 2008, Chinese paleontologist Lü Junchang and colleagues would use the term "Tupuxuaridae" to include both genera in their phylogenetic analysis, finding the group nested within Neoazhdarchia.

[5] Phylogenetic analyses by Brian Andres in 2014 and 2021 would support this model, finding a relationship between Thalassodromidae and Dsungaripteridae within Neoazhdarchia, a conclusion also found by a 2018 study.

In 2018, paleontologist Nicholas Longrich and colleagues recovered the pterosaurs Aerotitan and Alanqa as thalassodromids, but noted that their fossil remains of are fragmentary, so this assignment was only tentative.

They also expressed skepticism at the result of Leptosomia and Xericeps as thalassodromids, noting their fragmentary nature and concluding it was difficult to be certain of their position within Azhdarchoidea.