Thames Centre is a municipality in Middlesex County, Ontario, Canada, directly east of the City of London.

[3] It was formed on January 1, 2001, when the townships of West Nissouri and North Dorchester were amalgamated.

[4] It is part of the London census metropolitan area.

Thames Centre includes the Degree Confluence of 43N 81W.

Communities in the township include: Avon, Belton, Cherry Grove, Crampton, Cobble Hill, Derwent, Devizes, Dorchester, Evelyn, Fanshawe Lake, Friendly Corners, Gladstone, Harrietsville, Kelly Station, Mossley, Nilestown, Oliver, Putnam, Salmonville, Silvermoon, Thorndale (mayor - John Fluttert), Three Bridges, and Wellburn.