His father migrated from Vietnam and met his mother in Kentucky, before the family moved to New Orleans, Louisiana, when he was 5 years old.
On August 31, 2015, it was announced that Le would be a contestant on the 22nd season of The Ultimate Fighter reality show, representing Team Faber.
[4] Le represented Team Faber in the first preliminary fight of the season facing Sweden's Martin Svensson.
[10] Le faced former ONE Lightweight World Champion Kotetsu Boku on August 16, 2019, at ONE: Dreams of Gold.
[14] Le faced Martin Nguyen for the ONE Featherweight World Championship on October 30, 2020, at ONE: Inside the Matrix.
[23] The rematch between Le and Tang for the ONE Featherweight World Championship was scheduled on July 15, 2023, at ONE Fight Night 12.
[25] Le faced Ilya Freymanov for the interim ONE Featherweight World Championship on October 7, 2023, at ONE Fight Night 15.
[29] Le faced Tang Kai in a rematch, for the ONE Featherweight World Championship unification bout on March 1, 2024, at ONE 166.