The second season was announced to be split-cour anime, with the first part originally set to premiere in October 2020, but it was instead delayed to January 2021 due to production complications resulting from the COVID-19 pandemic.

Crazed and half awoke as a True Demon Lord, Clayman plans to kill Rimuru to keep his title.

However, Rimuru simply pummels and devours Clayman instead; learning the Moderate Harlequin Alliance works for former Demon Lord Kazeream, whose body Leon killed to take his spot, but was reincarnated as Kagali.

This forces Luminous to remove her disguise and send Roy back to her domain to deal with the intruder lurking there while expressing annoyance at Veldora for blowing her cover.

Carrion and Frey give up their seats as Demon Lords upon seeing they are too weak; while still ruling their lands, they now work for Milim, though she isn't happy with this.