Suzanne Vale, an actress with bipolar disorder, married Leland Franklin, a studio executive who helped her find her "far-flung best self."

Three years later, Vale is a successful TV talk show host with a six-year-old daughter, a gay ex-husband, and an aging starlet mother.

When Vale, a recovering drug addict, stops taking her medication, she is plunged into a manic episode.

She goes on a search for OxyContin in Tijuana with a tattoo artist friend and a new house guest, a clinically depressed patient she met at her psycho-pharmacologist's office.

Despite her mental illness, Vale still has her wit and ability to find irony in every situation as she struggles back from the brink of insanity.