The album was issued in several versions with different track inclusion and running order which varied slightly between North American and international editions of The Best of Blondie, highlighting the popularity of particular songs in different countries.

The international version of the album included three songs that were not on the North American release: "Denis", "Picture This" and "Union City Blue".

[6][7][8] Blondie's producer Mike Chapman remixed three tracks specially for this album.

[citation needed] The album cover was shot in June 1978 by British photographer Martyn Goddard on a rooftop in Midtown Manhattan.

In addition to the entirety of The Best of Blondie, this DVD also includes three bonus tracks not on the original release: "The Hardest Part", "Island of Lost Souls", and "Maria".