The Biggest Thing Since Colossus is an album by American blues musician Otis Spann, released in 1969.

The album is also notable for the fact that Spann's backing band on this occasion were members of Fleetwood Mac, who were touring in America at the time.

Guitarists Peter Green and Danny Kirwan, and bassist John McVie all contributed to the sessions.

[1] "Walkin'" was released as a single in some countries, with "Temperature Is Rising (98.8°F)" (a different version to that found on the album) on the B-side.

[4] An expanded version was released in 2006 on a double CD (Otis Spann, The Complete Blue Horizon Sessions) with all tracks from the sessions plus the single "Bloody Murder" and both single and album versions of "Temperature is Rising".