The Case of Jennie Brice is a 1913 crime novel by the American writer Mary Roberts Rinehart (1876–1956) set in 1904 in Allegheny, Pennsylvania, which has been a part of the city of Pittsburgh since 1907.

A blood-stained rope, and towel, and a missing tenant, Jennie Brice—all of which convince Mrs. Pittman that a murder has been committed in her boarding house.

Pittman tries to ferret out the killer by using the key to Jennie's apartment to investigate.

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