[3] In 1974, The Comedy Store hosted the wedding reception of newlyweds Liza Minnelli and Jack Haley, Jr.

The Comedy Club signage was covered, for the evening, by signs reading "Ciro's", denoting the venue's prior identity.

The event was attended by many dozens of Hollywood glitterati, including Elizabeth Taylor, Sammy Davis Jr., Cher, Bob Fosse, Johnny Carson, Goldie Hawn, Cesar Romero, Priscilla Presley and other stars, past and present.

[9][10][11][12][13][14] Beginning in 1979, The Comedy Store served for many years as the host location for the annual HBO Young Comedians specials.

Tension between the club owners stems from a 1979 strike of Los Angeles comedians against the Comedy Store's "no-pay policy".

She alleged that comedians came to the club and could work on their material in front of casting agents and other talent scouts who would possibly hire them as professionals if they were good enough.

After the strike, some comedians were no longer allowed to perform at the club, including Steve Lubetkin, who committed suicide by jumping off the roof of the Continental Hyatt House next door.

The union ceased to exist in 1980, although from the time of the job action onward, comedians in Los Angeles were paid for their shows.

"When she and Sammy divorced in 1974, he gave her the club to lower his alimony payments; two years later, after being briefly evicted (and opening a new Comedy Store location in Westwood), she negotiated a deal to buy the entire building — plus Cresthill...around the time of Lubetkin’s suicide(After a bitter labor dispute between comedians and management[19]), she essentially gave the place over to the comedians who worked at the Store.

During the 1980s, numerous comedians resided or just partied there, including Andrew Dice Clay, Marc Maron, Robin Williams, and Richard Pryor.

Mitzi Shore had a plan to cash in on the house's unique atmosphere, and even shot a 12-minute pilot around 1987 starring Daphne Davis, Nancy Redman, and Tamayo Otsuki.