The manuscript, written in the 1920s, was originally titled The Mad Brain.

With permission of his widow, Forrest J Ackerman edited it, modernizing the manuscript to remove some of the "anachronisms" of the 1920s.

[1] The novel concerns Patricia Lane who is in love with Nicholas Devine, a quiet and gentle writer.

Frightened by this, Lane consults psychologist Dr. Carl Horker, who rescues her from Devine while under the influence of one of his spells.

He is then shot by Lane and rushed to a hospital where a second brain is discovered and removed.