Set in Las Vegas, Nevada, the show involves a pair of defense attorneys who go all out to help their clients while keeping their personal lives in order.

The show is loosely based on real-life Vegas lawyers Michael Cristalli and Marc Saggese.

[5] In January 2011, CBS announced that The Defenders was moving from its Wednesday timeslot to the Friday timeslot vacated by Medium which aired on NBC and then CBS for seven seasons, with Blue Bloods temporarily moving to the timeslot The Defenders vacated.

Blue Bloods returned to its Friday timeslot in February 2011 owing to the series premiere of Criminal Minds: Suspect Behavior.

[6] Jim Belushi and Jerry O'Connell star as the defense attorneys of the show's title.