After the master's death in 1520, they worked together with other members of Raphael's workshop to finish the commission to decorate with frescoes the rooms that are now known as the Stanze di Raffaello, in the Apostolic Palace in the Vatican.

It was inspired by the famous forged documents that supposedly granted the Popes sovereignty over Rome's territorial dominions.

The painting depicts an apocryphal historical event: Emperor Constantine kneels before Pope Sylvester I and offers the Pope and his successors control of the city of Rome and the entire Western Roman Empire.

In the center background of the painting is the altar with its twisted, Solomonic columns.

These columns were a gift from Constantine who supposedly took them from the ruined Jewish temple.