Its present location at 101st Street and 100th Avenue was established in 1921, and Alberta's first radio station, CJCA, began broadcasting from the building a year later.

[2] In 1937, the Journal came into conflict with Alberta Premier William Aberhart's attempt to pass the Accurate News and Information Act requiring newspapers to print government rebuttals to stories the provincial cabinet deemed "inaccurate".

After successfully fighting the law, the Journal became the first non-American newspaper to be honoured by the Pulitzer Prize committee, receiving a special bronze plaque in 1938 for defending the freedom of the press.

In 1982, government officials under the Combines Investigation Act entered and searched the paper's offices under the suspicion that Southam Newspapers was violating federal legislation by engaging in unfair trading and anti-competitive business practices.

[9] The Alberta Court of Appeal ruled the search to be inconsistent with the Charter of Rights and Freedoms, a decision the Supreme Court of Canada upheld in Hunter v Southam Inc.[10] Today, the Journal publishes six days a week, with regular sections including News (city, Canada, and world), Sports, Opinion, A&E, Life, and Business.