The Fifth Patient is a 2007 American thriller film written and directed by Amir Mann, and starring Nick Chinlund and Marley Shelton.

John Reilly, an American national, finds himself in an African hospital where, he learns he has spent the last two years due to a head injury.

Las Vegas Weekly stated: "This is an immediate and engrossing set-up, similar to the basic template for plenty of thrillers, and it lends The Fifth Patient a certain momentum that lasts more than halfway through the film, until writer-director Mann starts providing some answers about why exactly his main character (Chinlund) is in Africa, and what his mysterious tormentors and/or allies are trying to get out of him.

As the possible spy begins to regain bits and pieces of his memory, along the way becoming more confident in his own espionage skills, the film resembles The Bourne Identity on a smaller scale."

A review in Variety also found that "the guessing games lose their intrigue since the underlying mystery is suspiciously thin".