The Final Nexus is a 1988 science fiction novel by American writer Gene DeWeese, part of the Star Trek: The Original Series franchise.

It was a sequel to the previous book by DeWeese within the franchise, Chain of Attack.

In The Final Nexus, the warp-gates that the Enterprise have been using to traverse the universe is now malfunctioning.

The Enterprise must communicate with creatures from different worlds and universes in an attempt to fix the gates.

This article about 1980s novels and other printed work relating to Star Trek is a stub.