[1] The series premiered on November 26, 2010, in six cities on Fox owned stations: New York on WNYW, Los Angeles on KTTV, Philadelphia on WTXF, Phoenix on KSAZ, Minneapolis on KMSP and Orlando on WOFL.

[2] The Fran Drescher Show was given a three-week trial run with the option of being nationally syndicated.

Drescher described what she would bring to the program: "I'm thrilled to be able to bring The Fran Drescher Tawk Show to daytime TV, which fits me hand in glove," and added that "It will cover all of my passions, everything from pedicures to politics.

I'm the girl next door, a self-made woman who has been to hell and back a few times.

"[6] The house band on the show was led by Foo Fighters and Wallflowers member Rami Jaffee.