First published in 1658, along with its companion Urn-Burial, in modern times it has been recognised as Browne's major literary contribution to Hermetic wisdom.
[2][3] The book begins with the biblical creation, allusions to Plato's discourse the Timaeus and speculation upon the location of the Garden of Eden.
[4] Written during a time when restrictions on publishing became more relaxed during Oliver Cromwell's Protectorate, The Garden of Cyrus is Browne's contribution to a "boom period" decade of interest in esoterica in England.
[5] Browne's discourse is a neoplatonic and neopythagorean vision of the interconnection of art and nature via the inter-related symbols of the number five and the quincunx pattern, along with the figure X and the lattice design.
[6] Its fundamental quest was of primary concern to Hermetic philosophy: proof of the wisdom of God, and demonstrable evidence of intelligent design.