When an elderly patient named Ana Martinez, who was being looked after by Amy and Charlie, suddenly dies, the hospital's administrative board contacts the state police, represented by detectives Danny Baldwin and Tim Braun.

However, the board, led by risk manager Linda Garran, quickly downplays it, claiming the death was unintentional and that the reason for reporting it was simply to abide by health protocol.

Parkfield finally shares its investigation with the police, but Baldwin notices that it is fragmentary, leading him to snap at Garran, causing him and Braun to be banned from the hospital.

Meanwhile, after Kelly Anderson, another ICU patient suffers a seizure and inexplicably dies, Amy discovers insulin had also been administered to her the night before.

They convince Kelly's husband to exhume her body in order to perform an autopsy; it reveals a dual combination of insulin and digoxin led to her death.

In an attempt to entice Charlie into disclosing his actions, Baldwin and Braun have Amy arrange a meeting with him, but he reacts aggressively when she asks about his dismissal from Parkfield.

The film was announced in November 2016, with Tobias Lindholm set to direct and Krysty Wilson-Cairns writing the screenplay adapting Charles Graeber's 2013 non-fiction book The Good Nurse: A True Story of Medicine, Madness, and Murder.

The website's consensus reads: "The Good Nurse is hobbled by stilted dialogue and unrealistic story elements, but those issues are offset by strong work from a pair of talented leads.

"[10] Metacritic, which uses a weighted average, assigned the film a score of 65 out of 100, based on 38 critics, indicating "generally favorable" reviews.