The single was credited to John Travolta and Olivia Newton-John and released via Polydor Records.

The megamix topped the charts of Australia and Spain and became a top-five hit in Denmark, Ireland, the Netherlands, Norway, and the United Kingdom.

The song peaked at number one in Australia and remained there for five weeks in May 1991.

"The Grease Megamix" was re-released on the 1996 compilation CD Pure Disco.

The single was not released commercially in the US, which made it ineligible to chart on the Billboard Hot 100; it did reach the top 40 on three of Billboard's radio format airplay charts.