The musical opened Off-Broadway at Bows at Dodger Stages on September 22, 2005, and starred Marya Grandy (Lin), Linda Hart (Betty), Shuler Hensley (Norbert), Kaitlin Hopkins (Jeannie), Leslie Kritzer (Pickles), Orfeh (Pippi), and Wayne Wilcox (Duke); Betsy Kelso is the director.

Directed and choreographed by Steven Smeltzer; starring Erica Livingston (Jeannie), David Howard (Norbert), Sara Ruzicka (Pippi), MaryAnne Piccolo (Lin), Lindsay Devino (Pickles), Dane Agostinis (Duke), Doreen Barnard (Betty), Kenneth D'Elia and Carolyn Kimmel (Swings).

The Great American Trailer Park Musical made its UK premiere with the same cast from the 1st National Tour at the Edinburgh Fringe Festival in 2008.

[4] In April 2010, the show had its New England premiere with the SpeakEasy Stage Company, with Leigh Barrett (Jeannie), Mary Callanan (Lin), Kerry A. Dowling (Betty), and David Benoit (Norbert).

[6][7] The Finger Lakes Musical Theatre Festival (Auburn, N.Y.) put on a production of the show from June 6 to July 14, 2013, with LilyAnn Carlson (Pickles), Kristen Gehling (Lin), Andy Lindberg (Norbert), Chelsey Whitelock (Betty), and Brooke Wilson (Jeannie).

Soon arriving in town is Pippi, a stripper on the run from her abusive boyfriend, hoping the drama at Armadillo Acres will distract everyone else from her plight to allow her to live in peace.